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State patient's age on the request form.
1 - 3 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Serum or plasma
0.2 mL (Note: This volume does not allow for repeat testing.)
Red-top tube, gel-barrier tube, or green-top (heparin) tube
Pediatric: Blood drawn from heelstick for capillary. Separate serum or plasma from cells as soon as possible after clot formation. Transfer specimen to a plastic transport tube.
Hemolysis; EDTA plasma submitted
Evaluate electrolyte and water balance, hyperosmolar status, and hydration status; evaluate dehydration, acid-base balance; evaluate seizures; clue to alcoholism, methanol toxicity, ethylene glycol ingestion; evaluate antidiuretic hormone function, liver disease, hyperosmolar coma, evaluate hypernatremia. Osmolarity measures the concentration of particles in solution.
Freezing point depression
Neonatal: may be as low as 266 mOsm/kg; 0 to 60 years: 275−295 mOsm/kg; 61 years and older: 280−301 mOsm/kg
High serum osmolality can result from hypernatremia, dehydration, hyperglycemia, mannitol therapy, azotemia, ingestion of ethanol, methanol, ethylene glycol. Thus, osmolality has a role in toxicology and in coma evaluation. Elevated serum osmolality with normal sodium suggests possible hyperglycemia, uremia, or alcoholism.1
Low serum osmolality may be secondary to overhydration, hyponatremia, syndrome of inappropriate antidiuretic hormone secretion (SIADH) with carcinoma of lung and other entities.
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