Creatine Kinase (CK) and Lactate Dehydrogenase (LD), Totals and Isoenzymes

CPT: 82550; 82552; 83615; 83625
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  • CK and LD Isoenzymes
  • CPK and LDH Isoenzymes
  • Lactate Dehydrogenase (LD) and Creatine Kinase (CK) Isoenzymes
  • LD and CK Isoenzymes
  • LDH and CK Isoenzymes

Special Instructions

State sex of patient on the test request form.

Expected Turnaround Time

4 - 7 days

Related Documents

Specimen Requirements




3 mL refrigerated serum and 3 mL room temperature serum


Red-top tube or gel-barrier tube

Storage Instructions

Creatine kinase: refrigerate. Lactate dehydrogenase: maintain specimen at room temperature. Do not freeze or refrigerate. Creatine kinase: stable refrigerated for 48 hours or frozen for two weeks. Lactate dehydrogenase: stable at room temperature for seven days or refrigerated for no more than three days.

Causes for Rejection

Creatine kinase: hemolysis. Lactate dehydrogenase: hemolysis; prolonged contact of serum with red cells; frozen specimen; specimen refrigerated more than three days after collection at time of testing.

Test Details


Evaluation of possible myocardial damage or other cardiac diseases. See individual test descriptions for CK Isoenzymes and LD Isoenzymes.


Total: kinetic; Isoenzymes: agarose gel electrophoresis with densitometry


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
001859 CK+LD, Totals+Isoenzymes 001362 Creatine Kinase,Total U/L 2157-6
001859 CK+LD, Totals+Isoenzymes 002164 Macro Type 2 % 26020-8
001859 CK+LD, Totals+Isoenzymes 002156 CK-MM % 15049-0
001859 CK+LD, Totals+Isoenzymes 002165 Macro Type 1 % 26019-0
001859 CK+LD, Totals+Isoenzymes 002157 CK-MB % 12187-1
001859 CK+LD, Totals+Isoenzymes 002158 CK-BB % 15048-2
001859 CK+LD, Totals+Isoenzymes 001115 LDH IU/L 14804-9
001859 CK+LD, Totals+Isoenzymes 011866 (LD) Fraction 1 % 2536-1
001859 CK+LD, Totals+Isoenzymes 011874 (LD) Fraction 2 % 2539-5
001859 CK+LD, Totals+Isoenzymes 011882 (LD) Fraction 3 % 2542-9
001859 CK+LD, Totals+Isoenzymes 011890 (LD) Fraction 4 % 2545-2
001859 CK+LD, Totals+Isoenzymes 011908 (LD) Fraction 5 % 2548-6

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