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Creatinine, urine; thallium, urine; thallium:creatinine ratio
Monitor industrial exposure to thallium
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Inductively-coupled plasma/mass spectrometry (ICP/MS)
• Environmental exposure: <0.0−1.5 μg/L
• Thallium:creatinine ratio: 0.0−0.9 μg/g creatinine1
Thallium exposure, associated with industrial inhalation and/or dermal absorption of metallic thallium or thallium salts, may cause albuminuria, sensory changes, polyneuritis, speech disturbances, weakness, and visual impairment. Ingestion of soluble thallium salts is characterized by colic, nausea, vomiting, tremors, and paralysis.2 Thallium compounds are employed in semiconductor research, optical systems, and photoelectric cells. Thallium salts are also used as insecticides and rodenticides. Poisoning from occupational exposure to thallium can occur in the manufacture of optical instruments, rodenticides, dyes, and certain alloys. Environmental exposure may follow emissions from smelters, cement plants, and coal-fired plants.
Urine (random or 24-hour)
Plastic urine container, no preservative
Optional protocol: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Avoid contact with metal during collection. Screw the lid on securely.
Maintain specimen at room temperature.
Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both a routine urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|706580||Thallium, Urine||706581||Thallium, Urine||ug/L||21558-2|
|706580||Thallium, Urine||706584||Thallium/Crt Ratio||ug/g crt||13469-2|