Tetanus Antitoxoid Antibodies

CPT: 86317
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Synonyms

  • Tetanus Toxin Antibodies

Expected Turnaround Time

1 - 5 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.5 mL


Container

Red-top tube or gel-barrier tube


Storage Instructions

Room temperature; do not freeze.


Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

Unstable

Freeze/thaw cycles

Unstable


Causes for Rejection

Gross hemolysis; lipemia; bacterial contamination


Test Details


Use

Assess immunity against tetanus by determining levels of circulating antibodies to tetanus toxin or to measure the immune response, postvaccination, in individuals suspected of immunodeficiency disorders


Limitations

Determination of tetanus toxoid antibodies is of no value in assessing the need for prophylactic or therapeutic management. Immunity declines with age, and boosters are recommended every 10 years.

This procedure may be considered by Medicare and other carriers as investigational and, therefore, may not be payable as a covered benefit for patients.


Methodology

Enzyme immunoassay (EIA)


Reference Interval

Nonprotective: <0.1 IU/mL


References

Gergen PJ, McQuillan GM, Kiely M, et al. A population-based serologic survey of immunity to tetanus in the United States. N Engl J Med. 1995; 332(12):761-766. 7862178
Rose NR. Manual of Clinical Immunology. 5th ed. Washington, DC: ASM Press;1997: 470-472.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
163691 Tetanus Antitoxoid IgG Ab 53935-3 163694 Tetanus Antitoxoid IgG Ab IU/mL 53935-3

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