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Expected Turnaround Time
2 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Lavender-top (EDTA) tube
Trough: 30 minutes to one hour before the next oral dose
Causes for Rejection
Monitor immunosuppressive therapy following organ transplant
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
Sirolimus may be administered in conjunction with cyclosporine (CsA) and corticosteroids to reduce or prevent host graft rejection. Using this therapy, peak concentrations are achieved in one to two hours. The mean terminal elimination half-life is 62 hours.1 Drug-drug interactions, including CsA, may alter the pharmacokinetics of sirolimus, making therapeutic drug monitoring appropriate.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|716712||Sirolimus (Rapamune), Blood||29247-4||716713||Sirolimus, Blood||ng/mL||29247-4|