Sedimentation Rate, Modified Westergren

CPT: 85652
Print Share

Test Details

Synonyms

  • Erythrocyte Sedimentation Rate
  • ESR
  • Westergren Sedimentation Rate

Use

Evaluate the nonspecific activity of infections, inflammatory states, autoimmune disorders, and plasma cell dyscrasias

Limitations

Optimum results are from blood less than two hours old. The ESR is of limited diagnostic value in severe anemia or in hematologic states that affect increased size and shape variation (poikilocytosis) of the RBC (ie, presence of sickle cells or spherocytes). Extreme plasma viscosity will result in a decreased ESR.

Methodology

Modified Westergren; automated and manual methods are employed.

Reference Interval

• Male: 0 to 50 years: 0−15 mm/hour, 50 years and older: 0−30 mm/hour

• Female: 0 to 50 years: 0−32 mm/hour, 50 years and older: 0−40 mm/hour

Additional Information

Elevations in fibrinogen, α- and β-globulins (acute phase reactants), and immunoglobulins increase the sedimentation rate of red cells through plasma. The test is important in the diagnosis of temporal arteritis, as well as its management.1

Specimen Requirements

Specimen

Whole blood

Volume

Tube fill capacity

Minimum Volume

2 mL

Container

Lavender-top (EDTA) tube

Collection

Invert tube immediately 8 to 10 times once tube is filled at time of collection.

Storage Instructions

Refrigerate

Stability Requirements

Temperature

Period

Refrigerated

24 hours

Causes for Rejection

Hemolysis; clotted specimen; underfilled tube; specimen older than 24 hours; improper labeling; transfer tubes with whole blood; specimen received in any anticoagulant other than EDTA; specimen diluted or contaminated with IV fluid; patient specimen with presence of cold agglutinins or cryoglobulins; specimen received with plasma removed

Clinical Information

Footnotes

1. Wong RL, Korn JH. Temporal arteritis without an elevated erythrocyte sedimentation rate. Case report and review of the literature. Am J Med. 1986; 80(5):959-964.3518441

References

Gambino SR, Dire JJ, Monteleone M, et al. The Westergren sedimentation rate using K3 EDTA. Tech Bull Regist Med Technol. 1965; 35:1-8.
Harmening D. Clinical Hematology and Fundamentals of Hemostasis. 2nd ed. Philadelphia, Pa: Lippincott;1992:532-534.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
005215 Sedimentation Rate-Westergren 4537-7 005215 Sedimentation Rate-Westergren mm/hr 4537-7

For Providers

Please login to order a test.

 

© 2017  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf