Ovarian Cancer Monitor

CPT: 86304; 86305
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Test Includes

Human Epididymis Protein 4 [081700]; Cancer Antigen 125 [002303]. See individual test descriptions for complete information.


Special Instructions

This test may exhibit interference when sample is collected from a person who is consuming a supplement with a high dose of biotin (also termed as vitamin B7 or B8, vitamin H, or coenzyme R). It is recommended to ask all patients who may be indicated for this test about biotin supplementation. Patients should be cautioned to stop biotin consumption at least 72 hours prior to the collection of a sample.


Expected Turnaround Time

1 - 3 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.8 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or gel-barrier tube


Collection

If red-top tube is used, transfer separated serum to a plastic transport tube.


Storage Instructions

Refrigerate


Stability Requirements

Temperature

Period

Room temperature

5 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3


Test Details


Use

Use of HE4 in combination with CA 125 provides a more accurate predictor of malignancy than either marker alone.


Methodology

HE4: enzyme-linked immunosorbent assay (ELISA); CA 125: electrochemiluminescence immunoassay (ECLIA)


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
081610 Ovarian Cancer Monitor 002321 Cancer Antigen (CA) 125 U/mL 10334-1
081610 Ovarian Cancer Monitor 081750 HE4 pmol/L 55180-4

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