1p,19q Oncology FISH

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Test Details

Synonyms

  • Astrocytoma
  • Brain Tumor
  • FISH
  • Glioblastoma
  • Oligodendroglioma

Use

Confirmation/identification of cancer-related alterations (associated with oligoglioma)

Methodology

Fluorescence in situ hybridization (FISH) from formalin-fixed paraffin-embedded (FFPE) tissue (4-micron to 5-micron sections); H&E for pathology review.

Specimen Requirements

Specimen

Formalin-fixed paraffin block or fresh tissue (acceptable at additional charge)

Volume

Five slides (4- to 5-micron thick sections)

Minimum Volume

Three slides (4- to 5-micron thick sections)

Container

Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal

Collection

Transport to the testing lab at room temperature; if fresh tumor specimen, sample must arrive in the laboratory within 72 hours of collection.

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Improper embedded prep; poor fixation <6 hours and >72 hours; decalcified tissue; broken or dirty slides; absence of tumor or quantity not sufficient for analysis.

Clinical Information

Special Instructions

There will be an additional charge for processing paraffin block samples or for samples that require culture.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
510360 1P, 19Q Oncology FISH 510427 Specimen Type 31208-2
510360 1P, 19Q Oncology FISH 510428 Cells Counted N/A
510360 1P, 19Q Oncology FISH 510429 Cells Analyzed N/A
510360 1P, 19Q Oncology FISH 510357 FISH Result 48674-6
510360 1P, 19Q Oncology FISH 510437 Interpretation 50398-7
510360 1P, 19Q Oncology FISH 510359 Director Review: 48672-0
510360 1P, 19Q Oncology FISH 510219 1P 19Q FISH, Putaway N/A

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The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf