1p,19q Oncology FISH

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Test Details


  • Astrocytoma
  • Brain Tumor
  • FISH
  • Glioblastoma
  • Oligodendroglioma


Confirmation/identification of cancer-related alterations (associated with oligoglioma)


Fluorescence in situ hybridization (FISH) from formalin-fixed paraffin-embedded (FFPE) tissue (4-micron to 5-micron sections); H&E for pathology review.

Specimen Requirements


Formalin-fixed paraffin block or fresh tissue (acceptable at additional charge)


Five slides (4- to 5-micron thick sections)

Minimum Volume

Three slides (4- to 5-micron thick sections)


Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal


Transport to the testing lab at room temperature; if fresh tumor specimen, sample must arrive in the laboratory within 72 hours of collection.

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Improper embedded prep; poor fixation <6 hours and >72 hours; decalcified tissue; broken or dirty slides; absence of tumor or quantity not sufficient for analysis.

Clinical Information

Special Instructions

There will be an additional charge for processing paraffin block samples or for samples that require culture.

For Providers

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf