Nickel, Urine

CPT: 82570; 83885
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Test Details

Synonyms

  • Ni, Urine

Test Includes

Creatinine, urine; nickel, urine; nickel:creatinine ratio; nickel, urine (24-hour)

Use

Monitor exposure to nickel

Methodology

Inductively-coupled plasma/mass spectrometry (ICP/MS)

Reference Interval

Environmental exposure: 0.0−9.9 μg/g creatinine; 0.0−7.0 μg/24 hours

Occupational exposure (soluble compounds): 30 μg/g creatinine1

Specimen Requirements

Specimen

Urine (random or 24-hour)

Volume

5 mL

Minimum Volume

1.5 mL

Container

Plastic urine container, no preservative

Collection

Optional protocol: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Avoid contact with metal during collection. Screw the lid on securely.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Clinical Information

Special Instructions

State 24-hour volume on the request form, if applicable. Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.

Footnotes

1. Lauwerys RR, Hoet P. Industrial Chemical Exposure: Guidelines for Biological Monitoring. 2nd ed. Boca Raton, FL: Lewis Publishers.1993:292.

References

Baselt RC. Biological Monitoring Methods for Industrial Chemicals. 2nd ed. Littleton, Mass: Yearbook Medical Publishers;1988.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
071563 Nickel, Urine 071569 Nickel, Urine ug/L 14099-6
071563 Nickel, Urine 071572 Nickel, Urine (24hr) ug/24 hr 5705-9
071563 Nickel, Urine 723280 Creatinine(Crt),U g/L 2161-8
071563 Nickel, Urine 071570 Nickel/Creat. Ratio ug/g creat 13472-6
Reflex Table for Creatinine(Crt),U
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 723284 Comment: 723284 Comment: N/A

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