Nickel, Plasma

CPT: 83885
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Test Details


Monitor exposure to nickel


Inductively coupled plasma/mass spectrometry (ICP/MS)

Reference Interval

Environmental exposure: 0.6−7.5 μg/L

Occupational exposure: Levels of 3.0−11.0 μg/L may be seen in refinery workers.

Additional Information

Nickel exposure is commonly evidenced by contact dermatitis.1 Nickel exposure may also affect pulmonary tissues, as seen by x-ray.2 In addition, nickel toxicity has been linked with central nervous system (CNS) depressant effects.1 Nickel is a component of many alloys; it is often used in metal plating and in the production of numerous electrical devices and in electronics. Exposure most often occurs in the industrial environment either through the inhalation of nickel dust or dermal contact with nickel compounds.

Specimen Requirements




2 mL

Minimum Volume

0.6 mL


Royal blue-top (EDTA) tube


Submit original unopened tube or serum or plasma removed from a royal blue-top tube, and transfer to a certified metal-free plastic transport tube (PeopleSoft N° 111166) for shipment to the laboratory.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements



Room temperature

14 days


14 days


14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Certified metal-free plastic transport tube not submitted

Clinical Information


1. Baselt RC, Cravey RH. Disposition of Toxic Drugs and Chemicals in Man. 4th ed. Chemical Toxicology Institute;1995.
2. Jacobs DS, DeMott WR, Oxley DK, et al. Laboratory Test Handbook With Key Word Index. 5th ed. Hudson, Ohio: Lexi-Comp Inc; 2001.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
071571 Nickel, Plasma 5702-6 071571 Nickel, Plasma ug/L 5702-6

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