Find Locations
For hours, walk-ins and appointments.Synonyms
- Susceptibility Testing
Test Includes
Susceptibility testing by minimum inhibitory concentration methodology. Identification is required to perform or provide an accurate interpretation for susceptibility testing; it will be done at an additional charge if not provided by the client.
Special Instructions
Please list drug(s) to be tested.
Expected Turnaround Time
4 - 7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
Specimen Requirements
Specimen
Pure culture of bacteria to be tested
Volume
Viable colonies
Container
Agar slant in screw-cap container packed as an etiologic agent and a swab transport inoculated with the isolate from a pure culture. Maintain subculture at submitting laboratory.
Collection
Bacterium derived from cultured clinical sample. Send pure culture on maintenance media. Maintain subculture at submitting laboratory.
Storage Instructions
Maintain culture at room temperature.
Causes for Rejection
Inappropriate specimen transport device; unlabeled specimen or name discrepancy between specimen and request label; specimen received after prolonged delay (usually more than 72 hours)
Test Details
Use
Determine minimum inhibitory concentration (MIC) susceptibility of a given organism to an antimicrobial agent
Limitations
Determination of MIC on fastidious organisms may be attempted. If the organism of interest fails to grow, it will usually be reported out as unable to grow for MIC. A disc diffusion susceptibility test (Kirby-Bauer) susceptibility will be reported (susceptible, indeterminate, resistant) if possible.
Methodology
Broth microdilution (MIC)
Reference Interval
Minimal inhibitory concentration (MIC) reported. Results may be qualitatively reported as susceptible (S), intermediate (I), or resistant (R).
References
Gill VJ, Witebsky FG, MacLowry JD. Multicategory interpretive reporting of susceptibility testing with selected antimicrobial concentrations. Ten years of laboratory and clinical experience. Clin Lab Med. 1989 Jun; 9(2):221-238. 2659242
Hindler JA, Thrupp LD. Interpretive guidelines for antimicrobial susceptibility test results: What do they mean? Clin Microbiol Newslet. 1989; 17:129-136.
National Committee for Clinical Laboratory Standards. Performance Standards for Antimicrobial Susceptibility Testing. Fourth Information Supplement. Villanova, Pa: NCCLS;1992. Document M100-S4.
Rosenblatt JE. Laboratory tests used to guide antimicrobial therapy. Mayo Clin Proc. 1991 Sep; 66(9):942-948. 1921504
Sherris JC. Antimicrobic susceptibility testing. A personal perspective. Clin Lab Med. 1989 Jun; 9(2):191-202. 2659240
Silver LL, Bostian KA. Discovery and development of new antibiotics: The problem of antibiotic resistance. Antimicrob Agents Chemother. 1993 Mar; 37(3):377-383. 8460908
Wilkowske CJ. General principles of antimicrobial therapy. Mayo Clin Proc. 1991 Sep; 66(9):931-941. 1681155
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 096388 | Min Inhibitory Conc (1 Drug) | 21070-8 | 096388 | Min Inhibitory Conc (1 Drug) | 21070-8 |
| Reflex Table for Min Inhibitory Conc (1 Drug) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 080647 | Result | 080649 | Result 1 | 43409-2 | |
| Reflex Table for Min Inhibitory Conc (1 Drug) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 080647 | Result | 080650 | Result 2 | 43409-2 | |
| Reflex Table for Min Inhibitory Conc (1 Drug) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 080647 | Result | 080651 | Result 3 | 43409-2 | |
| Reflex Table for Min Inhibitory Conc (1 Drug) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 080647 | Result | 080652 | Result 4 | 43409-2 | |
| Reflex Table for Min Inhibitory Conc (1 Drug) | ||||||
|---|---|---|---|---|---|---|
| Order Code | Order Name | Result Code | Result Name | UofM | Result LOINC | |
| Reflex 1 | 080647 | Result | 080653 | Antimicrobial Susceptibility | 21070-8 | |
© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.
CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf