Metabolic Syndrome Profile

CPT: 82947; 83718; 84478
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Synonyms

  • Insulin Resistance Syndrome
  • Reaven's Syndrome
  • Syndrome X

Test Includes

Glucose, plasma; HDL cholesterol; triglycerides


Expected Turnaround Time

Within 1 day


Related Documents


Specimen Requirements


Specimen

Serum and plasma


Volume

1 mL serum and 0.5 mL plasma


Minimum Volume

0.5 mL serum and 0.5 mL plasma (Note: This volume does not allow for repeat testing.)


Container

Gel-barrier tube, transport tube, or green-top (heparin) tube and gray-top (sodium fluoride) tube


Collection

Separate serum or plasma from cells within 45 minutes of collection. Label gray-top tube as plasma.


Storage Instructions

Maintain specimen at room temperature.


Stability Requirements

Temperature

Period

Room temperature

3 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x2


Patient Preparation

Patient should be fasting for 12 to 14 hours and on a stable diet for two weeks prior to blood collection.


Causes for Rejection

Gross hemolysis; nonfasting specimen; specimen collected in glycerin tube; improper labeling


Test Details


Use

Identify individuals with metabolic syndrome. The National Cholesterol Education Program, Adult Treatment Panel III guidelines indicate that metabolic syndrome is present in patients with any three of the following five symptoms:

• HDL <40 mg/dL in men and <50 mg/dL in women

• Triglycerides ≥150 mg/dL

• Glucose ≥110 mg/dL

• Blood pressure ≥130/85

• Waist circumference >40” in men and >35” in women

Metabolic syndrome conveys an increased risk of diabetes, hypertension, gallbladder disease, osteoarthritis, and cardiovascular disease.


Limitations

This profile should not be performed on patients who have, in the preceding three months, suffered a myocardial infarction or similar traumatic episode, including acute infection or inflammation.


Methodology

Enzymatic


References

Mokdad AH, Ford ES, Bowman BA, et al. Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA. 2003 Jan 1; 289(1):76-79.12503980
National Heart, Lung, and Blood Institute. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Bethesda, Md: National Heart, Lung, and Blood Institute, National Institutes of Health; 2001. NIH Publication 02-5215.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
335884 Metabolic Syndrome Profile 001820 Glucose, Plasma mg/dL 2345-7
335884 Metabolic Syndrome Profile 001174 Triglycerides mg/dL 2571-8
335884 Metabolic Syndrome Profile 011820 HDL Cholesterol mg/dL 2085-9
335884 Metabolic Syndrome Profile 001821 See below: N/A
Reflex Table for HDL Cholesterol
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 011819 Comment 011819 Comment N/A

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