CPT: 80339
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Test Details


  • Vimpat®


Lacosamide is a functional amino acid specifically synthesized as an anticonvulsant drug. In addition to being approved for use as adjunctive therapy in the treatment of partial-onset seizures, it is being investigated as a treatment for diabetic neuropathic pain.


This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).


Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Specimen Requirements


Serum or plasma


0.25 mL

Minimum Volume

0.10 mL


Red-top tube, lavender-top (EDTA) tube, or green-top (heparin) tube. Do not use a gel-barrier tube. The use of gel-barrier tubes is not recommended due to slow absorption of the drug by the gel. Depending on the specimen volume and storage time, the decrease in drug level due to absorption may be clinically significant.


Transfer separated serum or plasma to a plastic transport tube.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements



Room temperature

14 days


14 days


105 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Gel-barrier tube

Clinical Information


Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS. Progress report on new antiepileptic drugs: A summary of the Ninth Eilat Conference (EILAT IX). Epilepsy Res. 2009 Jan; 83(1)1-43. 19008076
Krasowski M. Therapeutic drug monitoring of the newer anti-epilepsy medications. Pharmaceuticals (Basel). 2010 Jun 11; 3(6):1909-1935. 20640233


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
007012 Lacosamide 59297-2 007016 Lacosamide ug/mL 59297-2

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