Isohemagglutinin Titer

CPT: 86940
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Test Details

Synonyms

  • Anti-A Titer
  • Anti-B Titer
  • Isoagglutinins

Test Includes

Blood grouping; anti-A titer; anti-B titer; antibody screen

Use

Determine the titer of isohemagglutinins (anti-A and/or anti-B) in serum; the absence of expected isohemagglutinins may suggest an immunological deficiency. This test is not recommended for the determination of immunodeficiency. Dependent upon a variety of factors, normal titers are >1:8.

Limitations

The presence of cold agglutinins other than anti-A and anti-B may interfere with test interpretation. Newborns, infants younger than six months of age, and patients who have undergone immunosuppressive therapy may not demonstrate expected ABO isohemagglutinins.

Methodology

Hemagglutination

Specimen Requirements

Specimen

Whole blood

Volume

4 mL

Minimum Volume

3 mL

Container

Lavender-top (EDTA) tube

Storage Instructions

Refrigerate.

Causes for Rejection

Gross hemolysis; bacterial or other contamination

Clinical Information

References

Issitt PD, Anstee DJ. Applied Blood Group Serology. 4th ed. 1998.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
096164 Isohemagglutinin Titer 016428 Antibody Screen 18274-1
096164 Isohemagglutinin Titer 016445 Blood Grouping 883-9
096164 Isohemagglutinin Titer 016436 A Titer 30314-9
096164 Isohemagglutinin Titer 016444 B Titer 30201-8

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The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf