Isohemagglutinin Titer

CPT: 86940
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Test Details


  • Anti-A Titer
  • Anti-B Titer
  • Isoagglutinins

Test Includes

Blood grouping; anti-A titer; anti-B titer; antibody screen


Determine the titer of isohemagglutinins (anti-A and/or anti-B) in serum; the absence of expected isohemagglutinins may suggest an immunological deficiency. This test is not recommended for the determination of immunodeficiency. Dependent upon a variety of factors, normal titers are >1:8.


The presence of cold agglutinins other than anti-A and anti-B may interfere with test interpretation. Newborns, infants younger than six months of age, and patients who have undergone immunosuppressive therapy may not demonstrate expected ABO isohemagglutinins.



Specimen Requirements


Whole blood


4 mL

Minimum Volume

3 mL


Lavender-top (EDTA) tube

Storage Instructions


Causes for Rejection

Gross hemolysis; bacterial or other contamination

Clinical Information


Issitt PD, Anstee DJ. Applied Blood Group Serology. 4th ed. 1998.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
096164 Isohemagglutinin Titer 016428 Antibody Screen 18274-1
096164 Isohemagglutinin Titer 016436 A Titer 30314-9
096164 Isohemagglutinin Titer 016444 B Titer 30201-8
096164 Isohemagglutinin Titer 016445 Blood Grouping 883-9

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