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- Proinsulin:Insulin Ratio
The proinsulin:insulin ratio may be useful in managing type 2 diabetic patients. High basal proinsulin:insulin ratio in noninsulin-dependent diabetic patients may predict acute beta-cell dysfunction.
Prolonged IV glucose challenges in normal and obese subjects can produce significant increases in proinsulin:insulin ratios. Plasma/serum must be frozen due to the lability of insulin.
Immunochemiluminometric assay (ICMA)
Serum (preferred) or plasma, frozen
0.6 mL (Note: This volume does not allow for repeat testing.)
Separate serum or plasma from cells within 45 minute of collection. Send serum or plasma in a plastic transport tube. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Freeze; stable for 200 days. Stable at room temperature for six hours or refrigerated for 24 hours.
Causes for Rejection
Quantity not sufficient for analysis