Immunofixation (IFE) and Protein Electrophoresis, Cerebrospinal Fluid

CPT: 84157; 84166; 86335
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Synonyms

  • CSF IEP
  • CSF IFE
  • CSF Immunoelectrophoresis
  • CSF Immunofixation
  • Globulins, CSF
  • IFE/Protein Electrophoresis, CSF

Test Includes

Immunofixation of CSF; CSF protein electrophoresis


Special Instructions

The request form should include patient's age and clinical diagnosis.


Expected Turnaround Time

4 - 8 days


Related Documents

For more information, please view the literature below.

Published Plasma Cell Dyscrasias Selection Table


Specimen Requirements


Specimen

Cerebrospinal fluid (CSF)


Volume

5 mL


Minimum Volume

2 mL (Note: This volume does not allow for repeat testing.)


Container

Sterile container


Storage Instructions

Refrigerate


Causes for Rejection

Bloody CSF; less than 2 mL CSF


Test Details


Use

Evaluate possible multiple sclerosis, subacute sclerosing panencephalitis, and other chronic CNS disorders associated with local IgG synthesis


Methodology

Agarose gel immunofixation (IFE); protein electrophoresis on agarose media


Reference Interval

Normal pattern


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
001438 IFE and PE, CSF 143800 IFE, CSF 13174-8
001438 IFE and PE, CSF 002055 Protein, Total, CSF mg/dL 2880-3
001438 IFE and PE, CSF 143826 Pre-Albumin, CSF % 13973-3
001438 IFE and PE, CSF 143834 Albumin, CSF % 13974-1
001438 IFE and PE, CSF 143842 Alpha-1-Globulin, CSF % 13972-5
001438 IFE and PE, CSF 143859 Alpha-2-Globulin, CSF % 13975-8
001438 IFE and PE, CSF 143867 Beta Globulin, CSF % 13976-6
001438 IFE and PE, CSF 143876 Gamma Globulin, CSF % 13977-4
001438 IFE and PE, CSF 122370 PDF 11502-2

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