Please login to order a test.
HLA B*57:01, Abacavir Hypersensitivity HLA Association Test
- Abacavir Hypersensitivity HLA Association
- HLA Antigen B*57:01
- HLA B*5701
- HLA B57
- HLA B5701
If you have questions, please telephone 800-533-1037 (HLA customer service) for assistance in selecting the proper HLA test for the patient.
Expected Turnaround Time
3 - 7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Whole blood or buccal swabs
7 mL whole blood or four buccal swabs
3 mL whole blood or four buccal swabs
Lavender-top (EDTA) tube or four buccal swabs in a sealed envelope (buccal swab kit). When submitting buccal swabs, please use a buccal swab kit provided by LabCorp. To obtain the buccal swab kit, please telephone 800-533-1037.
Maintain blood specimen at room temperature. Keep buccal swabs dry and at room temperature.
Causes for Rejection
Hemolysis; clotted specimen; insufficient amount of DNA on buccal swabs
Determine the presence of B57 antigen
Even with appropriate precautions, an occasional specimen may not be satisfactory for testing. In such cases, an additional specimen should be collected for testing.
This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).
Polymerase chain reaction (PCR)/sequence-specific oligonucleotide probes (SSOP)
This is a class I allele-specific test.
Abacavir hypersensitivity has been shown to be associated with the human leukocyte antigen (HLA) B*57:01 of the major histocompatibility complex (MHC). The MHC family of genes codes for a highly variable set of cell surface glycoproteins (HLAs) that play a critical role in presenting antigens to T cell receptors to elicit an immune response. The presence of the HLA-B*57:01 allele increases the susceptibility to abacavir hypersensitivity in several populations studied.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|006926||HLA B5701 Test||42358-2||006930||Result||42358-2|