Herpes Simplex Virus (HSV) Types 1/2 Phenotyping for Acyclovir Drug Resistance

CPT: 87252; 87253
Print Share

Test Details

Synonyms

  • Acyclovir Resistance HSV (Phenotype)
  • Zovirax® Resistance

Use

This test method uses a plaque reduction assay. It measures the extent to which various concentrations of acyclovir inhibit the growth of virus in cell culture. The concentration of drug which results in a 50% reduction in plaque formation induced by viral cytopathic effect (CPE) versus the no-drug control establishes an inhibitory dose (ID-50) drug concentration reportable value.

Specimen Requirements

Specimen

Actively-growing isolate (preferred) or eye, genital, oral, urethral, vesicle, or throat swab

Volume

One tube with media or one swab

Container

Isolate in tube with media capped tightly; swab in viral transport media

Storage Instructions

Maintain isolate at room temperature. Refrigerate viral transport media with swab.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
138370 HSV Acyclovir Resistance 8-Jan 138371 ID 50 = ug/mL 8-Jan

For Providers

Please login to order a test.

 

© 2018  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf