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Herpes Simplex Virus (HSV) Types 1/2 Phenotyping for Acyclovir Drug Resistance
- Acyclovir Resistance HSV (Phenotype)
- Zovirax® Resistance
This test method uses a plaque reduction assay. It measures the extent to which various concentrations of acyclovir inhibit the growth of virus in cell culture. The concentration of drug which results in a 50% reduction in plaque formation induced by viral cytopathic effect (CPE) versus the no-drug control establishes an inhibitory dose (ID-50) drug concentration reportable value.
Actively-growing isolate (preferred) or eye, genital, oral, urethral, vesicle, or throat swab
One tube with media or one swab
Isolate in tube with media capped tightly; swab in viral transport media
Maintain isolate at room temperature. Refrigerate viral transport media with swab.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|138370||HSV Acyclovir Resistance||1-8||138371||ID 50 =||ug/mL||1-8|