Helicobacter pylori Culture

CPT: 87081; 87205
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Test Details

Synonyms

  • Campylobacter pylori
  • Campylobacter From Stomach
  • H pylori Culture
  • Culture, Helicobacter pylori

Test Includes

Culture; smear for modified Gram stain (reported only if positive and culture does not grow); isolation and identification (additional charges/CPT code[s] may apply). CPT coding for microbiology and virology procedures often cannot be determined before the culture is performed.

Use

Establish the presence and possible etiologic role of Helicobacter pylori in cases of chronic gastric ulcer, gastritis, duodenal ulcer, dyspepsia, etc

Methodology

Culture

Additional Information

For optimal recovery of Helicobacter pylori, it is strongly recommended that culture be performed within three hours of specimen collection. Helicobacter pylori has been implicated as a factor associated with chronic gastritis. The clinical significance of the organism in regard to gastric or duodenal ulcers, dyspepsia, and gastric carcinoma remains unclear.1 Other factors, such as pepsin, nonsteroidal anti-inflammatory agents (NSAIDs), aspirin, ischemia, stress, alcohol, and bile salts as well as H pylori, all may have a role in altering the material mucosal barrier. The relative etiologic role of H pylori remains a subject of speculation. H pylori is hypothesized to secrete products capable of degrading gastric mucin. The organism may be seen in Gram stains on imprints from tissue biopsies. In one study, imprint Gram stains performed by imprint technique on biopsies from both the antrum and fundus yielded positives in 100% of 32 culture-positive cases.2

Specimen Requirements

Specimen

Gastric material

Volume

Biopsy

Container

Anaerobic transport, aerobic/anaerobic bacterial swab transport system, CLO vial, urea agar medium

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Inappropriate specimen transport device; improper labeling; specimen received after prolonged delay (usually more than 72 hours)

Clinical Information

Footnotes

1. Clearfield HR. Helicobacter pylori: Aggressor or innocent bystander? Med Clin North Am. 1991 Jul; 75(4):815-829. 2072788
2. Parsonnet J, Welch K, Compton C, et al. Simple microbiologic detection of Campylobacter pylori.J Clin Microbiol. 1988 May; 26(5):948-949.3384915

References

Debongnie JC, Delmee M, Mainguet P, Beyaert C, Haot J, Legros G. Cytology: A simple, rapid, sensitive method in the diagnosis of Helicobacter pylori.Am J Gastroenterol. 1992 Jan, 87(1):20-23. 1728119
Dooley CP, Cohen H. The clinical significance of Campylobacter pylori.Ann Intern Med. 1988 Jan; 108(1):70-79. 3276266
Eastham EJ, Elliott TS, Berkeley D, Jones DM. Campylobacter pylori infection in children. J Infect. 1988 Jan; 16(1):77-79. 3367059
Marshall BJ. Should we now, routinely, be examining gastric biopsies for Campylobacter pylori? Gastric mucosal biopsy: An essential investigation in patients with dyspepsia. Am J Gastroenterol. 1988 May; 83(5):479-481. 3364408
Marshall BJ, Warren JR, Francis GJ, Langton SR, Goodwin CS, Blincow ED. Rapid urease test in the management of Campylobacter pyloridis-associated gastritis. Am J Gastroenterol. 1987 Mar; 82(3):200-210. 3548326
Taylor DN, Blaser MJ. The epidemiology of Helicobacter pylori infection. Epidemiol Rev. 1991; 13:42-59. 1765119
Veenendaal RA, Peña AS, Meijer JL, et al. Long term serological surveillance after treatment of Helicobacter pylori infection. Gut. 1991 Nov; 32(11):1291-1294.1752457

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
180885 Helicobacter pylori Culture 587-6 180885 Helicobacter pylori Culture 587-6
Reflex Table for Helicobacter pylori Culture
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080386 Result 080387 Result 1 N/A
Reflex Table for Helicobacter pylori Culture
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080386 Result 080388 Result 2 N/A
Reflex Table for Helicobacter pylori Culture
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080386 Result 080389 Result 3 N/A
Reflex Table for Helicobacter pylori Culture
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080386 Result 080390 Result 4 N/A
Reflex Table for Helicobacter pylori Culture
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 080386 Result 080391 Antimicrobial Susceptibility N/A

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