Glucose, Body Fluid

CPT: 82945
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Test Details

Use

Decreased fluid glucose concentration is usually associated with septic or inflammatory processes; in pleural effusion, very low glucose is a facet of rheumatoid effusion: pleural fluid glucose <50 mg/dL characterizes rheumatoid effusion. It is often much less.

Methodology

Enzymatic

Reference Interval

• Peritoneal: Not established

• Pleural:

− Transudate: Equal to simultaneously drawn plasma

− Exudate: Equal to simultaneously drawn plasma

• Synovial: Equal to simultaneously drawn plasma

The method performance specifications have not been established for this test in body fluid. The test result should be integrated into clinical context for interpretation.

Additional Information

Potts et al describe loculated effusions or empyemas with low glucose and low pH. Low glucose is found with empyema, tuberculosis, neoplasia, and rheumatoid effusion.1 In cases of malignant pleural effusions, when there is low pleural fluid glucose (<60 mg/dL) and pH <7.30, a probability of 90% that the cytologic yield will be positive was reported.2

Specimen Requirements

Specimen

Any fresh body fluid

Volume

1 mL

Minimum Volume

0.5 mL

Container

Sterile container

Patient Preparation

On synovial fluid collection only, patient should fast for eight hours.

Collection

Collect aseptically into sterile tube.

Storage Instructions

Room temperature

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Causes for Rejection

Improper labeling

Clinical Information

Special Instructions

The request form must state site of fluid (ie, pleural, peritoneal, pericardial, synovial).

Footnotes

1. Potts DE, Taryle DA, Sahn SA. The glucose-pH relationship in parapneumonic effusions. Arch Intern Med. 1978 Sep; 138(9):1378-1380. 28707
2. Rodríguez-Panadero F, López Mejías JL. Low glucose and pH levels in malignant pleural effusions. Diagnostic significance and prognostic value in respect to pleurodesis. Am Rev Respir Dis. 1989 Mar; 139(3):663-667. 2923367

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
019497 Glucose, Body Fluid 2344-0 019497 Glucose, Body Fluid mg/dL 2344-0

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