Estrone

CPT: 82679
Print Share

Test Details

Synonyms

  • E1

Use

Evaluate postmenopausal vaginal bleeding due to peripheral conversion of androgenic steroids. Increased estrone levels may be associated with increased levels of circulating androgens and their subsequent peripheral conversion.

Methodology

Radioimmunoassay (RIA)

Reference Interval

See table.1-3

Age (y)

Male (pg/mL)

Female (pg/mL)

0 to 5

18−53

19−46

6 to 7

17−48

17−44

8 to 9

20−54

31−70

10 to 11

21−49

28−68

12 to 14

17−44

57−140

Adults

12−72

Follicular: 37−138

Midcycle: 60−229

Luteal: 50−114

Postmenopausal: 14−103

Tanner Stage

I

5−17

4−29

II

10−25

10−33

III

15−25

15−43

IV

15−45

16−77

V

20−45

29−105

Specimen Requirements

Specimen

Serum or plasma

Volume

0.8 mL

Minimum Volume

0.4 mL (Note: This volume does not allow for repeat testing.)

Container

Red-top tube, gel-barrier tube, or lavender-top (EDTA) tube

Patient Preparation

No isotopes administered 24 hours prior to venipuncture.

Collection

If a red-top tube or lavender-top tube is used, transfer separated serum or plasma to a plastic transport tube.

Storage Instructions

Refrigerate

Causes for Rejection

Gross hemolysis; recently administered radioisotopes; lipemia; icteric specimen

Clinical Information

Special Instructions

Nonpregnant patients only.

Footnotes

1. Meites S, Buffone GJ, Cheng MH, et al, eds. Pediatric Clinical Chemistry, Reference (Normal) Values. 3rd ed. Washington, DC: AACC Press; 1989:123.
2. Ducharme JR, Forest MG, De Peretti E, et al. Plasma adrenal and gonadal sex steroids in human pubertal development. J Clin Endocrinol Metab. 1976; 42(3):468-476. 130382
3. Tietz NW, ed. Clinical Guide to Laboratory Tests. 3rd ed. Philadelphia, Pa: WB Saunders Co;1995:222.

References

Baird DT, Fraser IS. Concentration of oestrone and oestradiol in follicular fluid and ovarian venous blood in women. Clin Endocrinol (Oxf). 1975; 4(3):259-266. 1149301
Wright K, Robinson H, Collins DC, Preedy JR. Investigation of a radioimmunoassay for plasma estrone and estradiol-17-β in male and nonpregnant females. Comparison with an independent method using fluorometry. J Clin Endocrinol Metab. 1973 Jan; 36(1):165-173.4734134

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
004564 Estrone, Serum 2258-2 004564 Estrone, Serum pg/mL 2258-2

For Providers

Please login to order a test.

 

© 2017  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf