DNA Ploidy Analysis, Paraffin Block

CPT: 88182
Print Share

Test Details


  • DNA Histogram, Paraffin

Test Includes

DNA index; histogram interpretation


Cancer prognosis. In general, aneuploid tumors have an unfavorable prognosis compared to diploid tumors.


Use of fixatives other than formalin may not yield equivalent or satisfactory results. No % S phase is reported for tumors analyzed by image cytometry. Small biopsies require image analysis of a 6-μ tissue section. This test is not a diagnostic test for cancer.


Flow cytometry

Additional Information

The DNA index is a measure of the nuclear DNA content of tumor cells compared to normal cells. Tumors with abnormal DNA content are termed DNA aneuploid while those with DNA content equal to normal cells are termed DNA diploid.

Specimen Requirements


Formalin-fixed, paraffin-embedded (FFPE) tumor (tissue block)


One paraffin block


Paraffin block transport pouch


Specimen should be fixed in 10% neutral-buffered formalin. Optimum fixation time is 12 to 24 hours, not to exceed 48 hours.

Storage Instructions

Maintain specimen at room temperature.

Clinical Information

Special Instructions

Please direct any questions regarding this test to oncology customer service at 800-345-4363.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
480327 DNA Ploidy, Paraffin Block 487018 Tissue Site N/A
480327 DNA Ploidy, Paraffin Block 487002 Specimen Received N/A
480327 DNA Ploidy, Paraffin Block 487003 Method of Analysis N/A
480327 DNA Ploidy, Paraffin Block 487004 DNA Index (Population 1) 30912-0
480327 DNA Ploidy, Paraffin Block 487017 S Phase Interpretation N/A
480327 DNA Ploidy, Paraffin Block 487012 Ploidy Interpretation N/A
480327 DNA Ploidy, Paraffin Block 487026 Director Review 72486-4

For Providers

Please login to order a test.


© 2018  Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2018, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf