Cryptococcus Antibodies, Quantitative

CPT: 86641
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Test Includes

Titer


Expected Turnaround Time

3 - 8 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.5 mL


Container

Gel-barrier tube or red-top tube


Storage Instructions

Refrigerate. Specimen can be stored at 2°C to 8°C for 72 hours. Freeze for longer storage.


Causes for Rejection

Cerebrospinal fluid (CSF)


Test Details


Use

Aid in the diagnosis of cryptococcosis


Limitations

Usefulness of test is limited to the ability of the host to make antibodies in response to the infection. Negative results do not rule out infection.


Methodology

Cell agglutination


Reference Interval

Negative: <1:2


Additional Information

Agglutination titers ≥1:2 are suggestive of infection with Cryptococcus neoformans. Agglutinins may be detected early in the course of the disease but if the disease progresses, excess antigen may be produced which renders antibodies undetectable. With effective chemotherapy, the antigen titer declines and antibody may once again be demonstrated. Antibodies may persist for long periods even after cessation of chemotherapy.


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
082891 Cryptococcus Antibodies, Quant 6369-3 082891 Cryptococcus Antibodies, Quant 6369-3

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