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Celiac Antibodies tTG IgA, EMA IgA, Total IgA With Reflex to tTG IgG
- Endomysial Antibodies
- Tissue Transglutaminase (tTG) Antibodies
Aid in the diagnosis of gluten-sensitive enteropathies
Enzyme immunoassay (EIA); indirect immunofluorescence
Celiac disease is a gluten enteropathy occurring in both children and adults. The disease is probably underdiagnosed in that it may affect as much as 1% of the population in the US. The condition is characterized by a sensitivity to gluten (found in wheat, barley, and rye) that causes inflammation and atrophy of the villi of the small intestine, malabsorption, etc. This sensitivity to gluten may also be seen in dermatitis herpetiformis. Strict avoidance of gluten in the diet will control disease activity, and antibodies to serum markers will disappear with time.
Causes for Rejection
Reflex testing for tissue transglutaminase (tTG) IgG antibodies is performed if total IgA is decreased.
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|165142||Celiac Disease Panel||164997||Endomysial Antibody IgA||10362-2|
|165142||Celiac Disease Panel||164643||t-Transglutaminase (tTG) IgA||U/mL||31017-7|
|165142||Celiac Disease Panel||001784||Immunoglobulin A, Qn, Serum||mg/dL||2458-8|
|Reflex Table for Immunoglobulin A, Qn, Serum|
|Order Code||Order Name||Result Code||Result Name||UofM||Result LOINC|
|Reflex 1||164988||t-Transglutaminase (tTG) IgG||164989||t-Transglutaminase (tTG) IgG||U/mL||32998-7|