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- Beta Carotene
Confirm the diagnosis of carotenoderma; detect fat malabsorption; depressed carotene levels may be found in cases of steatorrhea.
High levels are useful to rule out steatorrhea but lower values lack specificity. There is poor sensitivity. High in the serum of those ingesting large amounts of vegetables. The gold standard for confirmation of a diagnosis of malabsorption remains fat measurement of a 72-hour stool specimen.
High-pressure liquid chromatography (HPLC)
Vitamin A serum levels do not correlate well with liver stores. Carotenemia may be confused with jaundice. It is also reported high with some cases of diabetes mellitus, myxedema, chronic nephritis, nephrotic syndrome,1,2 liver disease, hypothyroidism, type I, IIA, and IIB hyperlipoproteinemia, and in a group of amenorrheic hypogonadotropic women.1 An inverse relationship between serum β-carotene and the risk of bronchogenic squamous cell carcinoma is reported.3 The highest carotene levels are found in the serum of faddists ingesting large amounts of vegetables.4 Oral leukoplakia responds well to β-carotene therapy.5 Low β-carotene levels are associated with oral contraceptives and smoking.6
Serum, protected from light
Specimen should be free from hemolysis. Protect from light. Transfer specimen to amber plastic transport tube.
Causes for Rejection
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|001529||Carotene, Beta||2053-7||001529||Carotene, Beta||ug/dL||2053-7|