Bordetella pertussis Antibodies, IgG

CPT: 86615
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Test Details

Use

Establish evidence of infection/exposure to Bordetella pertussis, the causative agent of whooping cough

Methodology

Enzyme-linked immunosorbent assay (ELISA)

Reference Interval

• Negative: <0.95 index

• Equivocal: 0.95−1.04 index

• Positive: >1.04 index

Additional Information

Patients with acute infection develop IgG, IgM, and IgA antibodies to fimbrial agglutinogens, and IgM and IgA antibodies are probably diagnostic. Following vaccination, IgG and IgM antibodies can be demonstrated. IgG antibodies can only be used to diagnose acute infection when paired sera are available and a rise in antibody level can be demonstrated.

Specimen Requirements

Specimen

Serum

Volume

0.4 mL

Minimum Volume

0.2 mL

Container

Red-top tube or gel-barrier tube

Storage Instructions

Refrigerate. Serum samples can be stored at 2°C to 8°C for up to seven days.

Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
161745 B pertussis IgG Ab 9363-3 161751 B pertussis IgG Ab index 9363-3

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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2017, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf