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Establish evidence of infection/exposure to Bordetella pertussis, the causative agent of whooping cough
Enzyme-linked immunosorbent assay (ELISA)
• Negative: <0.95 index
• Equivocal: 0.95−1.04 index
• Positive: >1.04 index
Patients with acute infection develop IgG, IgM, and IgA antibodies to fimbrial agglutinogens, and IgM and IgA antibodies are probably diagnostic. Following vaccination, IgG and IgM antibodies can be demonstrated. IgG antibodies can only be used to diagnose acute infection when paired sera are available and a rise in antibody level can be demonstrated.
Red-top tube or gel-barrier tube
Refrigerate. Serum samples can be stored at 2°C to 8°C for up to seven days.
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|161745||B pertussis IgG Ab||9363-3||161751||B pertussis IgG Ab||index||9363-3|