Bone Marrow Aspiration and Biopsy

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Test Details


  • Bone Marrow Aspirate
  • Iron Stain, Bone Marrow

Test Includes

H and E stain; iron stain; Wright stain


Evaluate bone marrow morphology, erythropoiesis, myelopoiesis, myeloid:erythroid ratio, megakaryocytes, cellularity, and marrow iron stores; evaluate etiology of abnormalities of production of RBC, WBC, or platelets; establish the presence of various primary or secondary malignancies: myeloma, carcinoma, lymphoproliferative diseases, or myeloproliferative diseases; evaluate respiratory therapy of hematologic disorders

Additional Information

Marrow culture can make valuable contribution to study of fever of undetermined origin and possible systemic infection, in particular, histoplasmosis and tuberculosis.

Specimen Requirements


Bone marrow aspirate clot and/or biopsy, bone marrow aspirate smears, and peripheral blood smears


2 to 5 mL, at least 1 cm core of bone marrow (complete specimen), bilateral if for staging of lymphoma


Smeared slides are prepared and labeled at the bedside by a laboratory technologist. Biopsy and clot are placed in fixative by technologist. Bone marrow smears for enzyme histochemistry must be fixed immediately in 10% neutral buffered formalin, absolute methyl alcohol, or 40% formalin vapor. Fixative container must be labeled with patient's full name, room number, date, and time and the fixative employed.

Causes for Rejection

No marrow obtained

Clinical Information

Special Instructions

Must include clinical/laboratory information, clinical hematological diagnosis, and a recent CBC or peripheral blood in EDTA.


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
489900 Bone Marrow Tracking 490001 Peripheral Blood N/A
489900 Bone Marrow Tracking 490002 Bone Marrow N/A
489900 Bone Marrow Tracking 490004 Comment: 77202-0
489900 Bone Marrow Tracking 490005 Clinical Information N/A
489900 Bone Marrow Tracking 490006 Gross Description 22634-0
489900 Bone Marrow Tracking 490007 Peripheral Blood (Detail) N/A
489900 Bone Marrow Tracking 490008 Differential N/A
489900 Bone Marrow Tracking 490009 Bone Marrow Biopsy 51628-6
489900 Bone Marrow Tracking 490010 Clot Section N/A
489900 Bone Marrow Tracking 490013 Marrow Smears 51628-6
489900 Bone Marrow Tracking 490014 Iron Stains 38519-5
489900 Bone Marrow Tracking 490015 Reticulin Stain 10804-3
489900 Bone Marrow Tracking 490016 Immunostains 55229-9
489900 Bone Marrow Tracking 490017 Special Stains N/A
489900 Bone Marrow Tracking 490018 Addendum 35265-8
489900 Bone Marrow Tracking 490019 Resulting Path Name 19139-5
489900 Bone Marrow Tracking 490020 Clinician provided ICD9: 52797-8
489900 Bone Marrow Tracking 490021 Resulting ICD9: 52797-8
489900 Bone Marrow Tracking 490022 Indications for Study 42349-1
489900 Bone Marrow Tracking 490023 CPT Codes N/A

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