BCR-ABL1 Oncology, FISH

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Synonyms

  • ALL FISH
  • CML FISH

Special Instructions

Pertinent clinical diagnosis, previous cytogenetic studies, and probe of interest should be included with the specimen. Please provide targeted FISH probe and diagnosis.


Expected Turnaround Time

3 - 5 days



Related Documents


Specimen Requirements


Specimen

Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei or bone marrow touch prep slides. Blood, bone marrow, cerebrospinal fluid (CSF).


Volume

Fixed-cell pellet, three slides, 10 mL blood (adult), 5 mL blood (pediatric), or 3 mL bone marrow


Minimum Volume

Fixed-cell pellet from a cytogenetic analysis, two slides, 5 mL blood (adult), 1 mL blood (pediatric), or 1 mL bone marrow


Container

Green-top (heparin) tube, pediatric Vacutainer® (optimal), or lavender-top (EDTA) tube


Collection

Transport to the testing lab at room temperature; LabCorp transport kit. Do not allow sample to overheat or freeze.


Storage Instructions

Maintain specimen at room temperature.


Causes for Rejection

Broken or dirty slides; excessive cellular debris or stained slides/paraffin blocks; decalcified bone cores; frozen specimen


Test Details


Use

Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease.


Methodology

Fluorescence in situ hybridization (FISH)


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
511520 Oncology BCR/ABL1 FISH 511504 Specimen Type 31208-2
511520 Oncology BCR/ABL1 FISH 511505 Cells Counted 62361-1
511520 Oncology BCR/ABL1 FISH 511506 Cells Analyzed 62360-3
511520 Oncology BCR/ABL1 FISH 511507 FISH Result 62356-1
511520 Oncology BCR/ABL1 FISH 511508 Interpretation 62365-2
511520 Oncology BCR/ABL1 FISH 511509 Director Review: 48672-0
511520 Oncology BCR/ABL1 FISH 512123 PDF 51967-8

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