Aluminum, Urine

CPT: 82108; 82570
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Test Details

Synonyms

  • Al, Urine

Test Includes

Aluminum, urine; creatinine, urine; aluminum:creatinine ratio; aluminum, urine (24-hour)

Use

Monitor patients for prior and ongoing exposure to aluminum. Patients at risk include:

• Infants on parenteral fluids, particularly parenteral nutrition

• Burn patients through administration of intravenous albumin, particularly with coexisting renal failure

• Adult and pediatric patients with chronic renal failure who accumulate aluminum readily from medications and dialysate

• Adult parenteral nutrition patients (less so, recently)

• Patients with industrial exposure

Monitor dialysate and water to prepare dialysate to prevent aluminum toxicity in dialysis patients.

Methodology

Inductively coupled plasma/mass spectrometry (ICP/MS)

Reference Interval

Environmental exposure: 5−30 μg/L, 0−32 μg/24 hours

Aluminum:creatinine ratio: <50 μg/g creatinine

Occupational exposure: 150 μg/g creatinine (collected at end of shift)1

Specimen Requirements

Specimen

Urine (random or 24-hour)

Volume

5 mL

Minimum Volume

1.5 mL

Container

Plastic urine container, no preservative

Collection

Optional protocol: Instruct the patient to void at 8 AM and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24-hour collection period (ie, 8 AM the next morning). Avoid contact with metal during collection. Screw the lid on securely.

Storage Instructions

Maintain specimen at room temperature.

Stability Requirements

Temperature

Period

Room temperature

14 days

Refrigerated

14 days

Frozen

14 days

Freeze/thaw cycles

Stable x3

Clinical Information

Special Instructions

Do not use preservative. Preservatives used for routine analysis may contain mercuric oxide (ie, Stabilur), which interferes with all metal testing. If both urinalysis and metal testing are ordered, please submit a separate urine specimen (containing no additive) for the metal testing.

Footnotes

1. Lauwerys RR, Hoet P, Industrial Chemical Exposure: Guidelines for Biological Monitoring, 2nd ed, Boca Raton, FL: Lewis Publishers, 1993, 290.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
071555 Aluminum, Urine 071557 Aluminum, Urine ug/L 6929-4
071555 Aluminum, Urine 723280 Creatinine(Crt),U g/L 2161-8
071555 Aluminum, Urine 071560 Aluminum/Crt Ratio ug/g creat 13470-0
071555 Aluminum, Urine 071559 Aluminum,Urine 24 Hr ug/24 hr 26707-0
Reflex Table for Creatinine(Crt),U
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 723284 Comment: 723284 Comment: N/A

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