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- Alpha-2 Macroglobulin
α2-macroglobulin assay is of major significance in the differential diagnosis of nephrotic syndrome, where an elevated α2-macroglobulin:albumin ratio is indicative of postrenal hematuria. In patients with liver cirrhosis and diabetes, the level of α2-macroglobulin is found to be elevated.
In hyperfibrinolytic states, after major surgery, in septicemia and severe hepatic insufficiency, the measured levels of α2-macroglobulin are often low. Patients with acute pancreatitis exhibit low serum concentrations that correlate with the severity of the disease.
0.2 mL (adult), 0.1 mL (pediatric)
Red-top tube or gel-barrier tube
Separate serum from cells within 30 to 60 minutes after collection. Transfer specimen to a plastic transport tube.
Maintain specimen at room temperature.
Causes for Rejection
Gross hemolysis (>1000 mg/dL); gross lipemia that cannot be cleared by ultracentrifugation
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|122135||Alpha-2 Macroglobulins, Qn||1835-8||122136||Alpha-2 Macroglobulins, Qn||mg/dL||1835-8|