The following information explains the requirements for basic and postvasectomy semen analysis. Please review the collection instructions below. Then copy and complete the form below with the patient. A separate copy can be obtained from LabCorp.
Complete the information on the form below, place the form and specimen container in the bag, and give it to the employee in the reception area along with your doctor's written test order form.
Chain of custody is the term that refers to the process of providing documentation of specimen identification and handling from the time of collection to the completion of laboratory testing.
It is often appropriate to demonstrate that
In order to use chain of custody handling, specimens must be submitted with chain of custody request forms. To order chain of custody handling, contact your local LabCorp facility.
Successful cytogenetics studies depend on specimen sterility and cellular viability. Considerations for submitting blood, bone marrow, tissue, and amniotic fluid are provided as follows.
Blood, Bone Marrow, Tissue. If submitting blood, bone marrow, or tissue for cytogenetics testing, follow these guidelines.
1. Submit blood or bone marrow in sterile sodium heparin (green) tubes. Lithium heparin tubes (green) inhibit cell growth. Use a small pediatric tube for aspirates less than 4 mL in volume. This will help avoid heparin toxicity of the sample.
2. Submit fetal tissue, skin, or other biopsies in LabCorp transport medium, Hanks' Balanced Salt Solution, or Ringer's lactate. Do not expose specimen to formalin or other fixatives.
3. Only refrigerate specimens when sterility is questioned.
Amniotic Fluid. When submitting amniotic fluid for cytogenetics testing, please follow the guidelines presented.
1. Submit specimens in sterile plastic tubes. Do not transport amniotic fluid in a syringe due to risk of loss of specimen if plunger is depressed.
2. Maintain at ambient temperature. Do not freeze or refrigerate.
3. Do not use the following containers for amniotic fluid:
a. Glass tubes with rubber stoppers. Rubber is toxic to amniocytes.
b. Wide-mouth urine containers that are prone to leak and become contaminated.
4. When preparing to transport cytogenetics specimens, please follow these guidelines.
a. Transport immediately so specimens will reach the laboratory within 24 to 48 hours—or as indicated elsewhere in this Directory.
b. To facilitate turnaround time and communication between the laboratory and physicians, complete the chromosome analysis history and order form with all the information required and staple the appropriate test request form to it. The following items are especially important:
To maintain chain of custody for any paternity collection, the proper collection kit must be obtained by calling the paternity evaluation department in Burlington, NC, at 800-742-3944. The kit contains specific collection instructions.
1440 York Court Extension
Burlington, NC 27215
Attention: Department of Paternity Evaluation
Note: If for any reason blood specimens are inadequate for evaluation, LabCorp reserves the right to request additional specimens.
If there are any questions regarding the above information or any paternity testing issues, please call the paternity customer service representatives at 800-742-3944, option 3.
Note: Please examine specimen collection and transportation supplies to be sure they do not include expired containers.
This Directory notes Storage Instructions for each test and specimen type. These are based on ideal circumstances, where necessary resources are available, intended to assist in maintaining the specimens in optimal condition, and should be considered recommendations.
In contrast, Causes for Rejection notes the limits of acceptability for the specimen, in order to obtain reliable results, and should be viewed as requirements. These are based on particular considerations of each test.
In addition to the specific Causes for Rejection noted for each test, testing will not be performed on specimens received under the following circumstances:
Should testing not be possible due to any of these causes for rejection, you will be advised on the patient report of which tests were affected, and the reason the test could not be performed.
LabCorp provides specimen collection containers that may contain the following hazardous chemicals:
LabCorp will provide Safety Data Sheets (SDS) on initial delivery of a product containing these substances. If additional copies of these SDS are needed, please contact your local branch/port manager.
Note: Patient isolates are not to be submitted to LabCorp for testing needed to rule out any Centers for Disease Control and Prevention (CDC) Select Agents and Toxins. These isolates are to be forwarded directly to the appropriate public health laboratory, and the appropriate public health laboratory should be contacted in advance of that forwarding.
Instructions for Transporting Diagnostic Materials and Infectious Substances
The US Department of Transportation (DOT) in Title 49 of the Code of Federal Regulations (CFR), The International Civil Aviation Organization (ICAO), and the International Air Transport Association (IATA) regulate the transportation requirements of Category B Infectious Substances (formerly known as “diagnostic specimens” and “clinical specimens”), Category A Infectious Substances, and Patient Specimens. When the specific instructions for container types, volume requirements, causes for rejection, etc, listed in individual tests and/or profile descriptions are followed, this helps ensure compliance with these regulations.