Acquired Thrombophilia

Acquired Thrombophilia

The incidence of venous thrombosis increases dramatically with age. The rate of occurrences changes from approximately one per 100,000 individuals younger than 40 years of age to one per 1000 individuals older than 75.1 A number of acquired conditions that are associated with an increased risk of thrombosis have been identified. They are listed in the table. 2

Acquired Conditions Associated With Thrombosis

Antiphospholipid antibodies (see below)

Malignancy

Atrial fibrillation

Myeloproliferative disorders

Congestive heart failure

Nephrotic syndrome

Diabetes mellitus

Oral contraceptive therapy

Estrogen therapy

Paroxysmal nocturnal hemoglobinuria

Heparin-induced thrombocytopenia

Postoperative state

Hypertension

Pregnancy

Hyperviscosity

Thrombotic thrombocytopenic purpura

Immobilization

Trauma

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