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For hours, walk-ins and appointments.NfL is a well-studied blood biomarker test that is now widely available through Labcorp for assessing neuronal damage from neurodegenerative diseases and sports-related concussion.
Neurofilament light chain (NfL) is a neuron-specific protein routinely released into the extracellular space. NfL levels rise above baseline in response to neuronal injury and neurodegeneration. Thus, NfL has been widely studied for various conditions 1, and can be helpful for assessing patients for:
In symptomatic patients with subjective memory decline, NfL provides direct evidence for and can be a predictor of clinical progression.2
NfL can be used in conjunction with clinical observation, as a primary biomarker to assess return to play in concussed athletes.3-5
Amyotrophic Lateral Sclerosis (ALS)6,7, Multiple Sclerosis 1,8, Parkinson’s Disease 9,10, and Spinocerebellar Ataxias.11 In each of these, NfL has been a predictor of disease progression
NfL levels in healthy patients and are known to increase with age.12,13 Labcorp has established reference intervals by age groups to facilitate interpretation of NfL results.
We want to be your partner in neurology, clinically and scientifically.
If you have an idea for a collaborative study, we would be interested in discussing it with you.
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Characterized by progressive muscle loss and weakness, our tests can detect the genetic mutations that cause the most common forms.
While no single test can diagnose multiple sclerosis, lab tests may help doctors rule out other diseases and confirm a diagnosis.
The increasing prevalence of neurodegenerative diseases has fueled the need for advanced research into pharmaceutical solutions and related neuro biomarkers.