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HIV Drug Resistance Testing
Drug resistance testing provides HIV-1 antiretroviral susceptibility data to assist clinicians in the selection of the most effective treatment regimen for each patient.
HIV drug resistance testing capabilities
Labcorp provides genotypic testing and is the only company to provide HIV phenotypic testing, as well as combination genotypic/phenotypic testing for determining patient ARV susceptibility.
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Genotyping
Genotype testing provides a prediction of drug susceptibility based on a patient’s viral mutational profile.
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Phenotyping
Phenotype testing provides an assessment of drug susceptibility based direct observation of viral inhibition in the presence of drugs.
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Combination Phenotypic and Genotypic Testing
Combination geno/pheno testing provides the most complete view of drug susceptibility, combining the susceptibility calls of phenotyping with the mutational information gained derived from genotyping.
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Tropism Assays
Tropism testing assesses the mechanisms by which HIV gains access to CD4 cells when a CCR5 antagonist is being considered for treatment.
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Suppression Management
Suppression management is available for patients who have established viral suppression and who may have reason for regimen modification. Genotypic testing interrogating the viral archive along with tropism testing of the DNA compartment provide data to support treatment changes without treatment interruption.