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Samples sent to Monogram for testing.
5 - 8 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Whole blood or Labcorp buccal swab kit (buccal swab collection kit contains instructions for use of a buccal swab)
5 mL whole blood or Labcorp buccal swab kit
3 mL whole blood or two buccal swabs
Lavender-top (EDTA) tube or yellow-top (ACD) tube or buccal swab kit
Collect specimen in a lavender-top (EDTA) tube or yellow-top (ACD) tube or use a buccal swab kit. Ship whole blood specimen at room temperature or frozen. Ship buccal swab collection kit at room temperature.
Maintain whole blood specimen at room temperature or refrigerated for 7 days, frozen for 2 years. Maintain buccal swabs at room temperture or refrigerated for 2 months.
Hemolysis; quantity not sufficient for analysis; improper container; single buccal swab; wet buccal swab
CYP2C9 genotype testing is required to determine candidacy and the appropriate maintenance dosage for siponimod before treatment initiation. Siponimod is contraindicated in patients who have a CYP2C9*3/*3 genotype. Refer to the siponimod package insert for more details.
This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.
Real-time polymerase chain reaction (RT-PCR)
|Order Code||Order Code Name||Order Loinc||Result Code||Result Code Name||UofM||Result LOINC|
|512215||CYP2C9 Genotyping Siponimod||46724-1||512216||2C9 Genotype||46724-1|
|512215||CYP2C9 Genotyping Siponimod||46724-1||512217||Interpretation||79716-7|
|512215||CYP2C9 Genotyping Siponimod||46724-1||512218||Director Review:||69965-2|
|512215||CYP2C9 Genotyping Siponimod||46724-1||512219||51969-4|
|512215||CYP2C9 Genotyping Siponimod||46724-1||000000||MGRM Informed Consent Review||N/A|
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