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Beta Amyloid 42/40 Ratio, CSF

CPT: To be determined. Updates will be made when available.

Special Instructions

This test is not approved for NY state clients.


Related Documents


Specimen Requirements


Specimen

Cerebrospinal fluid (CSF)


Volume

8 mL


Minimum Volume

5 mL


Container

Sarstedt CSF Tube 62.610.018. Tube provided by Labcorp by request.


Collection

Collect cerebral spinal fluid (CSF) in Sarstedt CSF Tube 62.610.018. Tube must be filled 50% to 80% minimum.


Storage Instructions

Refrigerate immediately (preferred), within 8 hours.


Stability Requirements

Temperature

Period

Room temperature

8 hours

Refrigerated

8 days

Frozen

30 days

Freeze/thaw cycles

Stable x1


Causes for Rejection

Wrong tube type; not stored at proper temperature; quantity not sufficient


Test Details


Use

To indicate the ratio of beta-amyloid 42 proteins to beta-amyloid 40 proteins measured in the CSF to aid in the assessment of disease progression in patients with suspected or probable Alzheimer's disease.


Methodology

Chemiluminescent enzyme immunoassay (CLEIA)


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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf