Test Details
Methodology
See individual tests.
Result Turnaround Time
4 - 7 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Test Includes
aPTT; factor VIII activity; factor VIII chromogenic; pathologist interpretation
Use
This profile is appropriate for the evaluation of individuals suspected of or previously identified as having nonsevere (mild or moderate) hemophilia A, in order to determine if there is a twofold discrepancy in the one stage and chromogenic factor VIII activities as has been described in discrepant hemophilia A. Evaluation for nonsevere hemophilia A using a one stage (clot-based) activity assay only may lead to missed diagnosis or misclassification of disease severity.
Specimen Requirements
Specimen
Plasma
Volume
4 mL platelet-poor, frozen, citrated plasma divided into two tubes
Minimum Volume
2 mL
Container
Blue-top (sodium citrate) tube
Collection Instructions
Plasma must be separated from cells within three hours of venipuncture and plasma centrifuged a second time before being placed in plastic transport tubes. Freeze within four hours and keep frozen until testing is performed.
Storage Instructions
Freeze
Causes for Rejection
Noncitrated plasma; gross hemolysis; fibrin clot in plasma; sample received thawed
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 504297 | Non-Severe Hemophilia A Prof. | 500513 | APTT | sec | 14979-9 | |
| 504297 | Non-Severe Hemophilia A Prof. | 500666 | Factor VIII Activity | % | 3209-4 | |
| 504297 | Non-Severe Hemophilia A Prof. | 500193 | FVIII Chromogenic | % | 49865-9 | |
| 504297 | Non-Severe Hemophilia A Prof. | 500684 | Pathologist Interpretation | 21026-0 | ||
| Order Code | 504297 | |||||
| Order Code Name | Non-Severe Hemophilia A Prof. | |||||
| Order Loinc | ||||||
| Result Code | 500513 | |||||
| Result Code Name | APTT | |||||
| UofM | sec | |||||
| Result LOINC | 14979-9 | |||||
| Order Code | 504297 | |||||
| Order Code Name | Non-Severe Hemophilia A Prof. | |||||
| Order Loinc | ||||||
| Result Code | 500666 | |||||
| Result Code Name | Factor VIII Activity | |||||
| UofM | % | |||||
| Result LOINC | 3209-4 | |||||
| Order Code | 504297 | |||||
| Order Code Name | Non-Severe Hemophilia A Prof. | |||||
| Order Loinc | ||||||
| Result Code | 500193 | |||||
| Result Code Name | FVIII Chromogenic | |||||
| UofM | % | |||||
| Result LOINC | 49865-9 | |||||
| Order Code | 504297 | |||||
| Order Code Name | Non-Severe Hemophilia A Prof. | |||||
| Order Loinc | ||||||
| Result Code | 500684 | |||||
| Result Code Name | Pathologist Interpretation | |||||
| UofM | ||||||
| Result LOINC | 21026-0 |