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For hours, walk-ins and appointments.Synonyms
- Mn, Plasma
Expected Turnaround Time
2 - 4 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Related Documents
Specimen Requirements
Specimen
Plasma
Volume
2 mL
Minimum Volume
0.6 mL
Container
Royal blue-top (EDTA) tube
Collection
Separate plasma immediately, and transfer to a certified metal-free plastic transport tube (PeopleSoft N° 111166) for shipment to the laboratory.
Storage Instructions
Maintain specimen at room temperature.
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 14 days |
Freeze/thaw cycles | Stable x3 |
Causes for Rejection
Certified metal-free plastic transport tube not submitted
Test Details
Use
Evaluate industrial exposure
Limitations
In evaluating toxicity, the serum level may have returned to normal while neurological damage persists. In evaluating possible deficiency states, the human deficiency syndrome is poorly defined, making interpretation difficult. Levels are reportedly reduced mildly in epilepsy, and raised in hepatitis or jaundice. Manganese levels are 60% lower than normal in hemodialysis patients.
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.
Methodology
Inductively-coupled plasma/mass spectrometry (ICP/MS)
Reference Interval
Environmental exposure: <2.5 μg/L
Additional Information
Toxic exposure may occur from dry cells, fungicide (maneb), and in the steel industry or chemical industry. Manganese is present in the coloring agents for glass and soap, in paints, varnish, enamel, and in linoleum. It is used in the manufacture of chlorine gas and now in lead-free gasoline. Industrial manganese poisoning has been recognized since 1837. Some water supplies are sufficiently contaminated by manganese that endemic psychiatric and neurological disease is present.
References
Ferraz HB, Bertolucci PH, Pereira JS, Lima JG, Andrade LA. Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication. Neurology. 1988 Apr; 38(4):550-553. 3352909
Kondakis XG, Makris N, Leotsinidis M, Prinou M, Papapetropoulos T. Possible health effects of high manganese concentration in drinking water. Arch Environ Health. 1989 May-Jun; 44(3):175-178. 2751354
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 071589 | Manganese, Plasma | 5683-8 | 071589 | Manganese, Plasma | ug/L | 5683-8 |
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