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Chimerism Analysis With CD56 Cells (Transplant Monitoring)

CPT 81268
Synonyms
  • Cell Sorting CD56
  • Chimerism Analysis With Sorted NK Cells
  • Engraftment Monitoring Sorted NK Cells

Test Details

Methodology

Antibody-mediated positive selection of CD56 cells and separation with magnetic nanoparticles. DNA analysis by polymerase chain reaction (PCR) of short tandem repeats (STR)

Result Turnaround Time

3 - 5 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

For more information, please view the literature below.

Transplant Engraftment (Chimerism Testing)

Use

Monitor level of donor CD56 cells in the recipient (patient-host) of a stem cell transplant. Polymorphic loci determined in the preëngraftment testing are used as a reference for the evaluation.

Special Instructions

To schedule this test, you must telephone 800-533-1037, HLA customer service. Ship specimen to arrive in the laboratory between Monday and Friday.

Limitations

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).

Specimen Requirements

Specimen

Whole blood

Volume

6 mL

Minimum Volume

4 mL

Container

Yellow-top (ACD-A or ACD-B) tube

Storage Instructions

Maintain specimen at room temperature. Do not refrigerate or freeze.

Patient Preparation

None

Causes for Rejection

Improper collection tube (ie, EDTA or heparin); hemolysis; clotted specimen

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
176092 Chimerism Analysis CD56 Cells 17175-1 176154 Donor 1 17175-1
176092 Chimerism Analysis CD56 Cells 17175-1 176413 Donor 2 17175-1
176092 Chimerism Analysis CD56 Cells 17175-1 176414 Donor 3 17175-1
176092 Chimerism Analysis CD56 Cells 17175-1 176415 Donor 4 17175-1
Order Code176092
Order Code NameChimerism Analysis CD56 Cells
Order Loinc17175-1
Result Code176154
Result Code NameDonor 1
UofM
Result LOINC17175-1
Order Code176092
Order Code NameChimerism Analysis CD56 Cells
Order Loinc17175-1
Result Code176413
Result Code NameDonor 2
UofM
Result LOINC17175-1
Order Code176092
Order Code NameChimerism Analysis CD56 Cells
Order Loinc17175-1
Result Code176414
Result Code NameDonor 3
UofM
Result LOINC17175-1
Order Code176092
Order Code NameChimerism Analysis CD56 Cells
Order Loinc17175-1
Result Code176415
Result Code NameDonor 4
UofM
Result LOINC17175-1