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Chimerism Analysis With CD3 Cells (Transplant Monitoring)

CPT 81268
Synonyms
  • Cell Sorting CD3
  • Chimerism Analysis With Sorted Lymphoid Cells
  • Engraftment Monitoring Sorted Lymphoid Cells

Test Details

Methodology

Antibody-mediated positive selection of CD3+ cells and separation with magnetic nanoparticles. DNA analysis by polymerase chain reaction (PCR) of short tandem repeats (STR)

Result Turnaround Time

3 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Documents

For more information, please view the literature below.

Transplant Engraftment (Chimerism Testing)

Use

Monitor the level of donor CD3+ cells in the recipient (patient-host) of a stem cell transplant. Polymorphic loci determined in the preëngraftment testing are used as a reference for the evaluation.

Special Instructions

To schedule this test, you must telephone 800-533-1037, HLA customer service.

Limitations

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).

Specimen Requirements

Specimen

Whole blood

Volume

6 mL

Minimum Volume

2 mL

Container

Yellow-top (ACD-A or ACD-B) tube

Storage Instructions

Maintain specimen at room temperature. Do not refrigerate or freeze. Ship specimen to arrive in the laboratory between Monday and Friday.

Patient Preparation

None

Causes for Rejection

Improper collection tube (ie, EDTA or heparin); hemolysis; clotted specimen

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
176059 Chimerism Analysis CD3 Cells 176129 Donor 1 103157-4
176059 Chimerism Analysis CD3 Cells 176231 Donor 2 103157-4
176059 Chimerism Analysis CD3 Cells 176232 Donor 3 103157-4
176059 Chimerism Analysis CD3 Cells 176233 Donor 4 103157-4
Order Code176059
Order Code NameChimerism Analysis CD3 Cells
Order Loinc
Result Code176129
Result Code NameDonor 1
UofM
Result LOINC103157-4
Order Code176059
Order Code NameChimerism Analysis CD3 Cells
Order Loinc
Result Code176231
Result Code NameDonor 2
UofM
Result LOINC103157-4
Order Code176059
Order Code NameChimerism Analysis CD3 Cells
Order Loinc
Result Code176232
Result Code NameDonor 3
UofM
Result LOINC103157-4
Order Code176059
Order Code NameChimerism Analysis CD3 Cells
Order Loinc
Result Code176233
Result Code NameDonor 4
UofM
Result LOINC103157-4