Test Details
Methodology
Liquid chromatography with tandem mass spectrometry (LC/MS-MS)
Result Turnaround Time
1 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Use
Therapeutic drug management
Specimen Requirements
Specimen
Serum or plasma, frozen
Volume
3 mL
Minimum Volume
0.6 mL
Container
Red-top (no additive) tube or green-top (heparin) tube. Gel-barrier tubes are not recommended. Storage/Transport: Custom "Transfer for Bupropion Analysis" tube containing Sodium Citrate Monobasic (PeopleSoft N° 116538)
Collection Instructions
Centrifuge within 30 minutes of collection. Transfer separated serum or plasma to the "Transfer for Bupropion Analysis" tube containing sodium citrate monobasic (white powder). Mix well. Freeze.
Reference Range
Bupropion: 50−100 ng/mL; hydroxybupropion: 600−2000 ng/mL
Storage Instructions
Freeze immediately; ship frozen on dry ice.
Patient Preparation
Trough levels are most reproducible.
Causes for Rejection
Gel-barrier tubes; specimen received not frozen; specimen not received in Bupropion Analysis Tube containing Sodium Citrate Monobasic
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 811083 | Bupropion (Wellbutrin) | 811084 | Bupropion (Wellbutrin) | ng/ml | 6706-6 | |
| 811083 | Bupropion (Wellbutrin) | 811085 | Hydroxybupropion | ng/ml | 9418-5 | |
| Order Code | 811083 | |||||
| Order Code Name | Bupropion (Wellbutrin) | |||||
| Order Loinc | ||||||
| Result Code | 811084 | |||||
| Result Code Name | Bupropion (Wellbutrin) | |||||
| UofM | ng/ml | |||||
| Result LOINC | 6706-6 | |||||
| Order Code | 811083 | |||||
| Order Code Name | Bupropion (Wellbutrin) | |||||
| Order Loinc | ||||||
| Result Code | 811085 | |||||
| Result Code Name | Hydroxybupropion | |||||
| UofM | ng/ml | |||||
| Result LOINC | 9418-5 |