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Venlafaxine and Desmethylvenlafaxine, Serum or Plasma

CPT 80299
Synonyms
  • Effexor®

Test Details

Methodology

High-pressure liquid chromatography with ultraviolet detection (HPLC/UV)

Result Turnaround Time

7 - 10 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Use

Therapeutic drug management

Specimen Requirements

Specimen

Serum or plasma

Volume

3 mL

Minimum Volume

0.6 mL

Container

Red-top tube or green-top (heparin) tube. Gel-barrier tubes are not recommended.

Collection Instructions

Serum or plasma should be separated from cells within two hours of venipuncture. Submit serum or plasma in a plastic transport tube.

Reference Range

Expected concentrations for venlafaxine: 100−500 ng/mL; desmethylvenlafaxine: 200−400 ng/mL.

Storage Instructions

Submission/transport (<3 days): Room temperature. For storage beyond three days, specimen should be refrigerated or frozen.

Patient Preparation

Trough levels are most reproducible.

Causes for Rejection

Gel-barrier tubes

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
808514 Venlafaxine (Effexor) 808515 Venlafaxine ng/ml 9630-5
808514 Venlafaxine (Effexor) 808516 Desmethylvenlafaxine ng/ml 9628-9
Order Code808514
Order Code NameVenlafaxine (Effexor)
Order Loinc
Result Code808515
Result Code NameVenlafaxine
UofMng/ml
Result LOINC9630-5
Order Code808514
Order Code NameVenlafaxine (Effexor)
Order Loinc
Result Code808516
Result Code NameDesmethylvenlafaxine
UofMng/ml
Result LOINC9628-9