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Organic Acid Analysis, Urine

CPT: 83919
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Expected Turnaround Time

3 - 7 days


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Specimen Requirements


Specimen

Urine (random), frozen


Volume

10 mL


Minimum Volume

3 mL (Note: This volume does not allow for repeat testing.)


Container

Plastic urine container, no preservative


Storage Instructions

Freeze


Stability Requirements

Temperature

Period

Frozen

12 months


Causes for Rejection

Urine too dilute; quantity not sufficient for analysis


Test Details


Use

Urine organic acid testing is useful in the diagnosis and monitoring of patients with inborn errors of organic acid metabolism, inborn errors of amino acid metabolism, urea cycle defects, and defects of the mitochondrial respiratory chain.


Limitations

Organic acid analysis may fail to detect certain disorders that are characterized by minimal or intermittent metabolite excretion.

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).


Methodology

Gas chromatography/mass spectrometry (GC/MS)


References

Shapira E, Blitzer MG, Miller JB, et al. Biochemical Genetics: A Laboratory Manual. New York, NY: Oxford University Press;1989.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
716720 Organic Acid Analysis, Urine 716721 Organic Acid Interpretation 49287-6
716720 Organic Acid Analysis, Urine 716723 Contact: n/a
716720 Organic Acid Analysis, Urine 716722 Methodology: 49549-9
716720 Organic Acid Analysis, Urine 700480 Disclaimer: n/a

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