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C3 Complement (RDL)

CPT: 86160

Synonyms

  • Complement Component 3

Test Includes

This test is a component of ANA Profile 11, ANA Profile 12, ANA 12 Plus Profile, Vasculitis Panel.


Expected Turnaround Time

5 - 7 days


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Container

Gel tube or red-top tube


Collection

Separate serum from cells within one hour. Transfer to a plastic transport tube before freezing.


Storage Instructions

Store frozen or refrigerated.


Stability Requirements

Temperature

Period

Room temperature

4 days

Refrigerated

8 days

Frozen

8 days

Freeze/thaw cycles

Stable x1


Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic, icteric, non-serum specimen types


Test Details


Use

Measurement of C3 is used to detect individuals with inborn deficiency of this factor or those with immunologic disease in whom complement is consumed at an increased rate. These include lupus erythematosus, chronic active hepatitis, certain chronic infections, post-streptococcal and membranoproliferative glomerulonephritis, and others.


Methodology

Turbidimetry


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CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf