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ANCA Profile (RDL)

CPT: 83516(x2); 86255
83520(x2); 86255
83516(x2); 86255
Updated on 10/13/2021
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Synonyms

  • ANCA Profile
  • Anti-Neutrophil Cytoplasmic Panel

Test Includes

ANCA; Anti-MPO (Myeloperoxidase) Ab; Anti-PR-3 (Proteinase 3) Ab; c-ANCA ans p-ANCA are resulted if positive. Otherwise, ANCA is reported as negative. Anti-Nuclear Ab (ANA) by IFA is performed if ANCA positive.


Expected Turnaround Time

14 - 21 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

3 mL

3 mL

3 mL

3 mL

3 mL


Minimum Volume

2 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or gel-barrier tube


Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping.


Storage Instructions

Refrigerate.


Stability Requirements

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1


Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types


Test Details


Use

C-ANCA & P-ANCA resulted if positive, otherwise reported as ANCA Negative. PANCA confirmed on formalin fixed slides. ANA performed if ANCA positive to rule out false positive ANCA due to presence of ANA.


Limitations

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.


Methodology

Enzyme-linked immunosorbent assay (ELISA); Indirect fluorescent antibody (IFA)


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
520149 ANCA Profile (RDL) 520150 ANCA by IFA (RDL) 29641-8
520149 ANCA Profile (RDL) 520154 Anti-MPO Ab (RDL) Units 72515-0
520149 ANCA Profile (RDL) 520155 Anti-PR-3 Ab (RDL) Units 63311-5
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520187 C-ANCA (IFA-ETOH) 14277-8
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520189 P-ANCA (IFA-ETOH) 14278-6
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520191 P-ANCA (IFA-Formalin) 17357-5
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520074 Homogeneous Pattern 20398-4
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520076 Nucleolar Pattern 20399-2
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520233 Speckled Pattern 20401-6
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520234 Centromere Pattern 53993-2
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520235 Spindle Apparatus Pattern 53003-0
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520236 Nuclear Membrane Pattern 54006-2
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520237 Midbody Pattern 54155-7
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520238 Nuclear Dot Pattern 53998-1
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520239 PCNA Pattern 53006-3
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520240 Centriole Pattern 54151-6
Reflex Table for ANCA by IFA (RDL)
Order Code Order Name Result Code Result Name UofM Result LOINC
Reflex 1 520245 Positive ANCA Reflex 520073 Anti-Nuclear Ab by IFA (RDL) 42254-3
Reflex 2 520248 ANA Panel for ANCA 520241 Note: 77202-0

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