Anti-Ribosomal P Protein Ab (RDL)

CPT: 83516
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Synonyms

  • Anti-Ribosomal P Protein Ab
  • RPPA

Expected Turnaround Time

7 - 14 days


Related Documents


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or gel-barrier tube


Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.


Storage Instructions

Refrigerate or freeze.


Stability Requirements

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1


Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types


Test Details


Use

Ribosomal P antibodies (RPPA) are detected in 45-90% of patients with severe depression or psychosis due to SLE; 7-20% in non-psychotic SLE patients. RPPA are ocasionally found in Sjorgen's syndrome associated with SLE and CNS complications and uncommon in patients with scleroderma and overlap with SLE.


Methodology

Enzyme-linked immunosorbent assay (ELISA)


Reference Interval

<20 Units


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
520123 Anti-Ribosomal P Ab (RDL) 13636-6 520124 Anti-Ribosomal P Ab (RDL) Units 13636-6

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