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Anti-Soluble Liver Ag Ab (RDL)

CPT: 83520
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Synonyms

  • Anti-SLA Ab
  • SLA

Expected Turnaround Time

7 - 14 days


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or gel-barrier tube


Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.


Storage Instructions

Refrigerate or freeze.


Stability Requirements

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1


Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types


Test Details


Use

Anti-SLA antibodies aid in the diagnosis of conditions with elevated levels of SLA antibody including autoimmune hepatitis (AIH), type 2. AIH patients are generally divided into 2 groups based on the presence of specific autoantibodies. AIH type 1 (also referred to as classic, active chronic, lupoid, plasma cell, or autoimmune chronic active hepatitis) is the more common type of AIH.


Methodology

Enzyme-linked immunosorbent assay (ELISA)


Reference Interval

• Negative: <20 Units

• Equivocal: 20–25 Units

• Positive: >25 Units


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
520114 Anti-Soluble Liver Ag Ab (RDL) 12734-0 520115 Anti-Soluble Liver Ag Ab (RDL) Units 12734-0

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