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Anti-Sa Ab, IgG (RDL)

CPT: 83516
83520
83516
Updated on 09/30/2021
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Synonyms

  • ACV
  • Anti-Citrullinated Vimentin
  • SA
  • Vimentin

Test Includes

This test is a component of RAdx5, SeroNegRAdx3.


Expected Turnaround Time

10 - 12 days

10 - 12 days

10 - 12 days

10 - 12 days

10 - 12 days


Related Documents

For more information, please view the literature below.

Rheumatoid Arthritis: Novel Serologic Markers White Paper

For more information, please view the literature below.

Rheumatoid Arthritis: Novel Serologic Markers White Paper


Specimen Requirements


Specimen

Serum


Volume

1 mL


Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Container

Red-top tube or gel-barrier tube


Collection

Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.


Storage Instructions

Refrigerate or freeze.


Stability Requirements

Temperature

Period

Room temperature

7 days

Refrigerated

14 days

Frozen

60 days

Freeze/thaw cycles

Stable x1


Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types


Test Details


Use

Anti-Citrullinated Vimentin (Sa) antibodies are highly specific for rheumatoid arthritis (RA). They are found in early polyarthritis, can identify patients that are anti-CCP and IgM-RF antibody-negative, and predict a more aggressive RA disease course. Disappearance of anti-Sa IgG antibodies 3 months after initiation of treatment is associated with less radiographic progression.


Limitations

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.


Methodology

Enzyme-linked immunosorbent assay (ELISA)


LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
520081 Anti-Sa Ab, IgG (RDL) 54022-9 520096 Anti-Sa Ab, IgG (RDL) Units 54022-9

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