Anti-Sa Ab, IgG (RDL)

CPT: 83516
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  • ACV
  • Anti-Citrullinated Vimentin
  • SA
  • Vimentin

Test Includes

This test is a component of RAdx5, SeroNegRAdx3.

Expected Turnaround Time

7 - 10 days

Specimen Requirements




1 mL

Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Red-top tube or gel-barrier tube


Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions

Refrigerate or freeze.

Stability Requirements



Room temperature

7 days


14 days


60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types

Test Details


Anti-Citrullinated Vimentin (Sa) antibodies are highly specific for rheumatoid arthritis (RA). They are found in early polyarthritis, can identify patients that are anti-CCP and IgM-RF antibody-negative, and predict a more aggressive RA disease course. Disappearance of anti-Sa IgG antibodies 3 months after initiation of treatment is associated with less radiographic progression.


This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.


Enzyme-linked immunosorbent assay (ELISA)


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
520081 Anti-Sa Ab, IgG (RDL) 54022-9 520096 Anti-Sa Ab, IgG (RDL) Units 54022-9

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