Anti-TPO Ab (RDL)

CPT: 86376
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  • Anti-Thyroid Microsomal Peroxidase Ab
  • Thyroid peroxidaseantibodies
  • TPO
  • TPO Ab

Test Includes

This test is a component of ANA Profile 12, ANA 12 Plus Profile, Thyroid Autoantibody Panel.

Expected Turnaround Time

14 - 21 days

Related Documents

Specimen Requirements




1 mL

Minimum Volume

0.3 mL (Note: This volume does not allow for repeat testing.)


Red-top tube or gel-barrier tube


Separate serum from cells within one hour of collection. Transfer to a plastic transport tube before shipping. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.

Storage Instructions

Refrigerate or freeze.

Stability Requirements



Room temperature

7 days


14 days


60 days

Freeze/thaw cycles

Stable x1

Causes for Rejection

Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types

Test Details


In virtually all cases of Hashimoto’s disease and in the majority of Graves’ disease cases, Anti-TPO autoantibodies are elevated. High levels of Anti-TPO autoantibodies, in the context of the clinical presentation of hypothyroidism, confirms the diagnosis of Hashimoto’s disease.


Chemiluminescent Immunoassay


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
520018 Anti-TPO Ab (RDL) 8099-4 520036 Anti-TPO Ab (RDL) IU/mL 8099-4

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