CPT: Call client services.
Print Share

Special Instructions

Indicate pertinent clinical diagnosis and previous cytogenetic studies on the test request form. Note: This test number is used for tracking FISH specimens to the testing laboratory. Bill codes will be added when testing is complete based on the processes performed in the laboratory.

Expected Turnaround Time

3 - 5 days

Specimen Requirements


Blood, bone marrow, CSF, fixed-cell pellet from a cytogenetic analysis, two slides with metaphase and/or interphase nuclei.


10 mL blood (adult), 5 mL blood (pediatric), 3 mL bone marrow, fixed-cell pellet from a cytogenetic analysis, or four slides with metaphase and/or interphase nuclei.

Minimum Volume

5 mL blood (adult), 1 mL blood (pediatric), 1 mL bone marrow, fixed-cell pellet from a cytogenetic analysis, or one slide with metaphase and/or interphase nuclei. Note: minimum slide volumes may not allow for repeat testing.


Green-top (heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube


Transport to the testing laboratory at room temperature, use of a cool pack or a LabCorp transport kit is acceptable. Do not allow samples to overheat or freeze.

Storage Instructions

Room temperature

Causes for Rejection

Broken Vacutainer®; broken slides; stained slides; paraffin blocks; paraffin slides; decalcified bone cores; frozen specimen; quantity not sufficient for analysis

Test Details


Fluorescence in situ hybridization (FISH), acute myelocytic leukemia (AML), and PML/RARA


Molecular mutations below the resolution of FISH will not be detected. Will not detect regions not targeted by FISH probes in this panel.

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).


Fluorescence in situ hybridization (FISH)


Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
511834 PML/RARA FISH Panel 511835 CELS Counted 62361-1
511834 PML/RARA FISH Panel 511836 CELS Analyzed 62360-3
511834 PML/RARA FISH Panel 511837 FISH Result 48674-6
511834 PML/RARA FISH Panel 511838 Interpretation 77031-3
511834 PML/RARA FISH Panel 511839 Specimen Type 31208-2
511834 PML/RARA FISH Panel 511840 Director Review 48672-0

For Providers

Please login to order a test

Order a Test

© 2021 Laboratory Corporation of America® Holdings and Lexi-Comp Inc. All Rights Reserved.

CPT Statement/Profile Statement

The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at Additional information regarding LOINC® codes can be found at, including the LOINC Manual, which can be downloaded at